KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
6.36
Human Site:
T1112
Identified Species:
11.67
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
T1112
R
G
A
N
G
S
E
T
N
R
V
G
S
N
H
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
T1112
R
G
A
N
G
S
E
T
N
R
V
G
S
N
H
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
D618
S
L
I
A
T
R
E
D
Y
R
Q
V
L
R
D
Dog
Lupus familis
XP_536285
2273
247246
P588
Q
H
E
E
E
E
R
P
T
N
Y
S
I
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
N1111
G
T
S
G
S
E
T
N
R
M
G
S
S
H
A
Rat
Rattus norvegicus
P70478
2842
310514
E1109
S
R
G
T
N
G
S
E
T
N
R
M
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
N1117
G
A
N
N
A
E
P
N
R
V
G
S
G
H
G
Chicken
Gallus gallus
XP_001233411
2232
244958
V547
L
Q
Q
V
I
A
S
V
L
R
N
L
S
W
R
Frog
Xenopus laevis
P70039
2829
310863
S1118
Q
V
D
Q
S
R
V
S
S
N
L
S
N
N
S
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
E1056
P
G
Y
P
M
Y
T
E
G
S
S
E
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
A732
H
L
I
R
S
A
S
A
S
D
A
H
R
K
V
Honey Bee
Apis mellifera
XP_624558
2760
306907
R1073
S
D
L
Q
E
D
T
R
Q
R
N
L
L
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
G1241
Y
C
V
E
G
T
P
G
P
I
S
R
C
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
13.3
0
N.A.
6.6
0
N.A.
6.6
13.3
6.6
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
20
6.6
N.A.
13.3
20
40
6.6
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
8
16
0
8
0
0
8
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
8
0
0
8
0
8
0
8
0
0
0
0
16
% D
% Glu:
0
0
8
16
16
24
24
16
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
24
8
8
24
8
0
8
8
0
16
16
24
0
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
8
0
16
16
% H
% Ile:
0
0
16
0
8
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
8
% K
% Leu:
8
16
8
0
0
0
0
0
8
0
8
16
16
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
8
24
8
0
0
16
16
24
16
0
8
24
0
% N
% Pro:
8
0
0
8
0
0
16
8
8
0
0
0
0
0
0
% P
% Gln:
16
8
8
16
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
16
8
0
8
0
16
8
8
16
39
8
8
8
8
8
% R
% Ser:
24
0
8
0
24
16
24
8
16
8
16
31
31
16
24
% S
% Thr:
0
8
0
8
8
8
24
16
16
0
0
0
0
0
0
% T
% Val:
0
8
8
8
0
0
8
8
0
8
16
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
0
8
0
0
8
0
0
8
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _